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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
26.67
Human Site:
S246
Identified Species:
45.13
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S246
A
R
D
G
N
D
Y
S
L
G
L
T
P
T
G
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S246
A
R
D
G
N
D
Y
S
L
G
L
T
P
T
G
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
S246
A
R
D
G
N
D
Y
S
L
G
L
T
P
T
G
Dog
Lupus familis
XP_532028
914
101864
S328
G
R
D
G
C
E
Y
S
L
G
L
T
P
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
S246
A
R
D
G
N
D
Y
S
L
G
L
T
P
T
G
Rat
Rattus norvegicus
Q5FVG2
731
81700
S246
A
R
D
G
N
D
Y
S
L
G
L
T
P
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
P259
A
F
F
R
L
R
G
P
V
Q
K
S
S
S
R
Chicken
Gallus gallus
XP_422083
502
57358
R40
I
P
A
A
G
D
A
R
S
V
I
T
C
R
V
Frog
Xenopus laevis
NP_001080234
498
57093
A36
A
T
T
H
I
P
A
A
G
D
T
R
S
I
I
Zebra Danio
Brachydanio rerio
O57457
619
70690
A157
Y
D
P
Y
K
H
T
A
G
Y
V
S
E
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
H261
G
K
D
G
C
E
Y
H
L
G
L
T
P
T
G
Honey Bee
Apis mellifera
XP_623974
809
90976
S325
G
K
D
A
C
E
Y
S
L
G
L
T
P
T
G
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
S380
N
T
Q
S
I
D
S
S
R
Y
T
N
T
T
T
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
H241
G
R
D
A
Q
D
Y
H
L
G
L
T
P
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
100
80
N.A.
100
100
N.A.
6.6
13.3
6.6
0
N.A.
66.6
66.6
20
73.3
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
26.6
20
13.3
20
N.A.
80
80
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
8
22
0
0
15
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
22
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
65
0
0
58
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
22
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
29
0
0
50
8
0
8
0
15
65
0
0
0
0
65
% G
% His:
0
0
0
8
0
8
0
15
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
15
0
0
0
0
0
8
0
0
8
8
% I
% Lys:
0
15
0
0
8
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
65
0
65
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
36
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
8
8
0
0
8
0
8
0
0
0
0
65
0
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
50
0
8
0
8
0
8
8
0
0
8
0
8
15
% R
% Ser:
0
0
0
8
0
0
8
58
8
0
0
15
15
8
0
% S
% Thr:
0
15
8
0
0
0
8
0
0
0
15
72
8
72
8
% T
% Val:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
65
0
0
15
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _